Kim Kardashian West speaks out on Kanye West’s Bipolar Disorder Diagnosis

On Monday night, he tweeted allegations that Kardashian and her mom Kris Jenner had tried to “lock him up,” and on Tuesday night, he claimed that he had been considering divorcing his wife. A source recently told PEOPLE that West’s tweets, which coincide with his attempt at a presidential run, come amid a new cycle in the rapper’s bipolar disorder.

Kardashian, 39, addressed the news in a lengthy note posted to her Instagram Story on Wednesday morning, asking fans for “compassion” as she publicly addressed her husband’s diagnosis for the first time.

“As many of you know, Kanye has bipolar disorder,” she began. “Anyone who has this or has a loved one in their life who does knows how incredibly complicated and painful it is to understand. I’ve never spoken publicly about how this has affected us at home because I am very protective of our children and Kanye’s right to privacy when it comes to his health. But today, I feel like I should comment on it because of the stigma and misconceptions about mental health.”

West, 43, seemed to reference his wife’s statement before it was released, tweeting late Tuesday night, “Kriss and Kim put out a statement without my approval … that’s not what a wife should do.” He has since deleted the post.